THE DEFINITIVE GUIDE TO LIGAZ SLOTS

DNA ligases seal 5′-PO4 and three′-OH polynucleotide finishes through 3 nucleotidyl transfer techniques involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are important guardians of genomic integrity, and ligase dysfunction underlies human genetic disorder syndromes. Crystal structures of DNA ligases sure to nucleotide and